GitHub - ModelDBRepository/185328: Enhancing the HH eqs: simulations based on the first publication in Biophys J (Moore 2015)

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Enhancing the HH eqs: simulations based on the first publication in Biophys J (Moore 2015)

modeldb.science/185328

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Name		Name	Last commit message	Last commit date
Latest commit History 2 Commits
HHMkchan.mod		HHMkchan.mod
hhkchan.mod		hhkchan.mod
hhleak.mod		hhleak.mod
hhnachan.mod		hhnachan.mod
mosinit.hoc		mosinit.hoc
nto6K.nrm		nto6K.nrm
readme.html		readme.html
screenshot.jpg		screenshot.jpg

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<html><pre>
This is the readme for the model associated with the paper:

Moore JW (2015) Enhancing the Hodgkin-Huxley Equations: Simulations
Based on the First Publication in the Biophysical Journal.
Biophys J 109:1317-20

This code was supplied by John Moore and Michael Hines.

This model is written in NEURON which is freely available at
<a href="http://www.neuron.yale.edu">http://www.neuron.yale.edu</a>
and is required to run this model.

See help at <a href="https://senselab.med.yale.edu/ModelDB/NEURON_DwnldGuide.html">https://senselab.med.yale.edu/ModelDB/NEURON_DwnldGuide.html</a>
to download and run the model.

Start the simulation with the mosinit.hoc (see above link).

Once the simulation is running click the "Reset & Run" button. This
ran and graphed the voltage using the 4th power version of the K
channel. Then select "Keep Lines" in Graph[0] (can either click in the
box in the upper left corner of the graph below the title bar, or
right click, and then drag the mouse down to release on "Keep Lines").

Click the "Replace HH K channels with HHkM channels", and then click
"Reset & Run" again. This added a voltage trace using the n to the 6th
power version of the K channel (and no leak channel). Graph[0] should
now contain an image similar to Figure 2 in the paper:

<img src="./screenshot.jpg" alt="screen shot" width="550">
</pre></html>