GitHub - ModelDBRepository/266974: Cardiac models of circadian rhythms in early afterdepolarizations & arrhythmias (Diekman & Wei 2021)

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Cardiac models of circadian rhythms in early afterdepolarizations & arrhythmias (Diekman & Wei 2021)

modeldb.science/266974

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Name		Name	Last commit message	Last commit date
Latest commit History 2 Commits
Figure2.png		Figure2.png
Figure9B.png		Figure9B.png
README.txt		README.txt
diekman_wei_model.m		diekman_wei_model.m
reproduceFigure2.m		reproduceFigure2.m
reproduceFigure9B.m		reproduceFigure9B.m

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README file for code associated with the paper "Circadian Rhythms of Early Afterdepolarizations and Ventricular Arrhythmias in a Cardiomyocyte Model"

Diekman CO and Wei N (2021) Biophysical Journal, https://doi.org/10.1016/j.bpj.2020.11.2264

The equations for the single-cell version of the model are in "diekman_wei_model.m".
Run "reproduceFigure2.m" to produce the plot shown in Figure 2.

The 2-D spatial version of the model can be run with the code "reproduceFigure9B.m" which will reproduce the simulations shown in Figure 9B. See lines 76-79 of this script to adjust parameter settings and reproduce Figures 6 or 9A instead.