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A feasibility-seeking and superiorization toolbox tuned for radiotherapy planning

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SupPy - Python superiorization library

SupPy is a native python library for user-friendly setup and evaluation of superiorzation algorithms.

General introduction

The Superiorization Method(SM) uses feasibility-seeking algorithms, i.e., algorithms that aim at finding apoint in the intersection of a finite number of given closed convex sets, i.e.,( $ \text{find } \mathbf{x}\in C = \bigcap_i C_i $).

In the SM the feasibility-seeking algorithm must be "perturbation resilient" in the sense that convergence of the feasibility-seeking iterative process is retained even when such perturbations are inserted into this iterative process. Given is also a real-valued objective function $\phi$. In contrast to constrained optimization of this objective function over the feasible set C, the goal of the SM is not to find a constrained minimum point but rather to reach a feasible point with reduced (not necessarily minimal) objective function value compared with the objective function value of a feasible point that would have been reached by the feasibility-seeking only algorithm.

Further information and references on the SM can be found in papers listed in the bibliographic collection on the dedicated Webpage. For recent works that include introductory material on the SM see, e.g., [1], [2], [3]. A recent work on applying the SM to problems in intensity-modulated radiation therapy (IMRT) treatment planning appears here.

Installation

Install simply via pip:

pip install suppy

In general SupPy works on the CPU (numpy), as well as the GPU(cupy). The standard installation will not set up cupy. For installation check your CUDA version and the cupy installation guide.

Usage

SupPy is a modular library for building and running superiorization models. it allows for quick setup of feasibility seeking and superiorization algorithms.

Projections for simple structures like halfspaces or circles have dedicated implementations in the suppy.projections submodule and allow for visualization of the structure if they are 2D objects.

import numpy as np
from suppy.projections import HalfspaceProjection
a = np.array([1.,1.])
b = 3
halfspace = HalfspaceProjection(a,b)
halfspace.visualize()

To calculate the projection each Projection object has a dedicated function (which if possible changes the array in place):

x = np.array([4.,4.])
x_p = halfspace.project(x)

Combined projections

For more complex structures that are formulated as the intersection of multiple constraints implementations for standard methods (SequentialProjection,SimultaneousProjection) and combinations of the two (StringAveragedProjection,BlockIterativeProjection) are available.

import numpy as np
from suppy.projections import BallProjection,SequentialProjection
center_1 = np.array([1,1])
radius_1 = 2
center_2 = np.array([-0.5,-1])
radius_2 = 1
ball_1 = BallProjection(center_1,radius_1)
ball_2 = BallProjection(center_2,radius_2)
joined_projection = SequentialProjection([ball_1,ball_2])

For a single projection step of these methods the project function can be used again. However since one step often times is not enough to find a point in the intersection, an entire run is needed. This can be done by calling the solve method.

joined_projection.solve(np.array([3,3]))

Linear algorithms

For linear problems $Ax\leq b$ dedicated implementations are available (right now formulated as $lb \leq Ax \leq ub$). In general AMS, ARM(Automatic relaxation method) and a sequential ART3+ implementation are available.

import numpy as np
from suppy.feasibility import SequentialAMS
A = np.array([[1,1],[1,0]])
lb = np.array([-2,-2])
ub = np.array([2,2])
alg = SequentialAMS(A,lb,ub)
alg.solve(np.array([5.,5.]),max_iter = 100)

In general these algorithms have the same functions as the basic projections (solve(),project(),etc.) and can be used as part of joined projections.

Superiorization

For setting up superiorzation models a feasibility seeking algorithm as well as a perturbation scheme are required. For gradient step based perturbations this can be set up in the following way:

from suppy.perturbations import PowerSeriesGradientPerturbation

def objective(x):
    return 1/len(x)*(x**2).sum(axis = 0)

def gradient(x):
    grad = 1/len(x)*2*x
    return grad/np.sqrt(np.sum(grad**2))

pert = PowerSeriesGradientPerturbation(objective,gradient)

from suppy.superiorization import Superiorization

sup_model = Superiorization(alg,pert)
sup_model.solve(np.array([3,2]), 1000)

Funding and Development

SupPy was developed as part of the German-Israeli Cooperation in Cancer Research (Project Ca 216) Responsible for SupPy are:

  • Tobias Becher (DKFZ, Lead Developer & Research Fellow)
  • Prof. Yair Censor (University of Haifa, Principal Investigator / Scientific Lead)
  • Dr. Niklas Wahl (DKFZ, Principal Investigator / Scientific Lead)

Miscellaneous

The authors would like to thank Allex Veldman for making the suppy namespace available on PyPi.

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